30 days old

Scientist Induced Proximity Platform - Targeted Protein Degradation

Amgen
Thousand Oaks, CA 91360
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  • Job Code
    131780194
Amgen

Job ID: R-114300
Location: Thousand Oaks, CA, US

Amgen's Induced Proximity Platform (IPP) is seeking a collaborative Scientist to join our Targeted Protein Degradation group in Thousand Oaks, California. The IPP is charged with developing Amgen's newest drug modality aimed at Targeted Protein Degradation, including discovery of PROTACs and molecular GLUEs. The IPP is seeking a creative, emerging scientific leader to discover and develop novel therapies for cancer and other therapeutic areas.

The Scientist's primary responsibilities will be developing platforms and modalities to impact challenging targets across multiple therapeutic areas, including oncology and immuno-oncology.The IPP takes innovative, cross-discipline approaches, including targeted protein degradation, to tackle the toughest targets.

The successful candidate will lead a project to support discovery and development of novel therapeutic modalities based on Targeted Protein Degradation, including prospective discovery of small molecule molecular GLUEs.The candidate will set project goals and timelines, design, perform and analyze experiments, interact with team members across different departments and research sites, and communicate and present data to department leadership. The candidate will also inform departmental goals and strategy and will represent the department in various cross-functional activities including academic collaborations, external research evaluations, project teams, and scientific committees.The candidate will also be expected to contribute to the scientific community through conference presentations and impactful publications.

Basic Qualifications

Doctorate degree

OR

Master's degree and 4years ofrelevant scientific experience

OR

Bachelor's degree and 6years ofrelevant scientificexperience

Preferred Qualifications
  • Broad knowledge of cancer and cellular biology with demonstrated independent research eminencethrough first author publications in top journals
  • Specific expertise and a record of publicationin the biology andbiochemistry of post-translational modifications, preferably ubiquitination.
  • Research experience with biochemical, biophysical, molecular and cellular techniques, including enzyme and cell assay development, characterization of protein modification and turnover, and mechanistic studies of enzymes
  • Excellent organizational, interpersonal and communication skills
  • Flexibility to work in teams to achieve changing project goals and meet timelines

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology.

Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.



PI131780194
Posted: 2021-03-11 Expires: 2021-04-12

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Scientist Induced Proximity Platform - Targeted Protein Degradation

Amgen
Thousand Oaks, CA 91360

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